| Test: |
Fluorescent in situ hybridization – Haematological |
| Alternate names: |
FISH |
| Description: |
Hybridization of fluorescent test probe to specific locus on chromosome. |
| Clinical: |
Leukemia, MDS.
Probes available in this lab:
BCR/ABL; t(8;21); del 13q14; 14q32 break apart - myeloma, Burkitt's, mantle cell and follicular lymphomas; inversion 16; P53 (17p13); ATM (11q22); MLL (11q23); XX/XY - for sex-mismatched allografts
|
| Methodology: |
Cultured bone marrow cells, bone marrow aspirate smears and peripheral blood smears can be analysed. Denaturation, hybridization and post-hybridization. Analysis using fluorescent microscope. |
| Turn around time: |
4 days |
| Transit stability: |
Alert laboratory immediately if sample is to be cultured. |
| Comments: |
Transport medium available from the laboratory. Slides can be transported in a slide mailer. |
| Sample: |
Bone marrow |
| Type: |
Cytogenetics |
| Method: |
NOT GIVEN |
 |
|
| Consultant/scientist: |
Ms Theresa Ruppelt |
| Tel: |
021 4044508 |
| email: |
Theresa.Ruppett@NHLS.ac.za |
|
|
| Contact for results: |
Cytogenetic Results |
| Tel: |
021 404 4509 |
| email: |
xxx@xxx.xxx |
|
|
| Delivery address |
C17, Groote Schuur Hospital, Observatory, , 7935 |
| for samples: |
Cape Town |
